Naum Raskind
Pronouns: He/Him/His
Research Mentor(s): Marcin Cieslik, Assistant Professor
Research Mentor School/College/Department: Computational Medicine and Bioinformatics / Pathology, Michigan Medicine
Presentation Date: Thursday, April 22, 2021
Session: Session 2 (11am – 11:50am)
Breakout Room: Room 7
Presenter: 8
Abstract
Cancer-causing processes such as smoking and exposure to UV-light leave behind unique mutational signatures among the DNA of cancer patients. The analysis of mutational signatures in raw tumor data to produce/solidify a diagnosis would greatly benefit cancer patients and help streamline their prognosis. My project deals with the analysis of variant data obtained from tumor samples in order to determine which mutational signatures are present, utilizing technologies such as deconstructSigs, siglasso, and quadratic programming, as well as the well-established COSMIC mutational signatures.