Identifying Brain Edema in CT Scans Using Machine Learning – UROP Spring Symposium 2021

Identifying Brain Edema in CT Scans Using Machine Learning

Lydia Lee


Pronouns: She, her, hers

Research Mentor(s): Reza Soroushmehr, Research Investigator
Research Mentor School/College/Department: Department of Computational Medicine & Bioinformatics, Michigan Medicine
Presentation Date: Thursday, April 22, 2021
Session: Session 1 (10am-10:50am)
Breakout Room: Room 16
Presenter: 2

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Brain edema is the swelling of the brain as a result of traumatic brain injuries, strokes, tumors, and infections. This affects the patients cognitive and motor function and can lead to lasting adverse health risks and death. Early and accurate identification of edema can prevent these hazards. Studies have found that brain edema is difficult for clinicians to accurately identify, as it often blends in with other brain matter. Additionally finding a link between the volume of edema and the effect on the patient is considered valuable, but there is currently no standard software in place for this end. Even when clinicians are able to identify edema, they are not able to quantify the volume present. Convolutional neural networks were used for training the model to segment the edema region. Images from the PROTECT III collection at the University of Michigan hospital were used for this research. Some images were previously annotated by clinicians and these images were subsequently used in the process of training the machine learning model. The performance of the model was evaluated using quantitative techniques such as dice, sensitivity, specificity, accuracy, and AUC. The goal of this software is to decrease adverse effects and death related to brain edema by creating a system to quantitatively measure edema and make informed decisions on how to treat the patient based on the information collected.

Authors: Lydia Lee
Research Method: Computer Programming

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