Nanoparticles and bacteria – chasing data! – UROP Spring Symposium 2021

Nanoparticles and bacteria – chasing data!

Nicole Sorensen

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Pronouns: she/her

Research Mentor(s): Angela Violi, Professor
Research Mentor School/College/Department: Mechanical Engineering, College of Engineering
Presentation Date: Thursday, April 22, 2021
Session: Session 4 (2pm-2:50pm)
Breakout Room: Room 18
Presenter: 3

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Abstract

There is a vast amount of research currently available regarding the discovery of new nanoparticles and their effectiveness in terms of killing bacteria. However, much of the literature is highly unorganized and fails to address the question of whether the nanoparticles’ ability to kill bacteria would render it a useful antibiotic. To address this issue, this study has gathered 8000 papers regarding such nanoparticle research to date. Each paper is judged twice, once by a machine learning algorithm and once by a human researcher, to determine whether the data provided in terms of the nanoparticle-microbe interactions is sufficient. If the paper is approved, it is included in the nanoparticle-microbe database, where data regarding such nanoparticle-microbe interactions is extracted. As this research is ongoing, the database has yet to be completed. However, the completed database will likely serve as a basis for future researchers and standardize the amount and types of data that should be collected. Additionally, further research should be conducted upon the nanoparticles included in the database to determine their potential for antibiotic or antimicrobial use.

Authors: Nicole Sorensen, Sumeyra Emre, Angela Violi, J. Scott VanEpps
Research Method: Data Collection and Analysis

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