Siddhi Bhirud
Pronouns: she/her
Research Mentor(s): Bo Yang
Co-Presenter:
Research Mentor School/College/Department: Cardiac surgery / Medicine
Presentation Date: April 20
Presentation Type: Oral5
Session: Session 1 – 10am – 10:50am
Room: Breakout Room 4
Authors: Siddhi Bhirud, Bo Yang, Marc Titsworth, Nathan Graham
Presenter: 3
Abstract
Aortic type A dissection repair remains a highly complicated operation, but with arch replacement involved, the operation further increases in complexity. The extent of the aortic arch repair each patient must undergo to reduce the chances of reoperation remains unclear. This study involves an observational registry with retrospective medical record data of patients who had aortic dissection repair surgery at the University of Michigan Hospital. These patients were separated into groups based on the extent of their arch repair (hemiarch, zone 1, zone 2, zone 3). Preoperative, intraoperative, perioperative, and postoperative aortic measurements were collected from the CTs, ECHOs, or MRIs of these patients. This data was used to create growth curves to compare the growth between the four groups according to time. Intraoperative results indicate that zones 1-3 had increased cardiopulmonary bypass, cross-clamp, and hypothermic circulatory arrest times and also required more blood transfusion than hemiarch replacement patients. Perioperative results suggest that zone 3 had more reoperation for bleeding, but the outcomes were otherwise similar in the other groups. Postoperative results show no significant difference in aortic arch, descending aorta, and abdominal aorta growth rates, 10-year survival rates, or 10-year reoperation rates among the 4 cohorts. More aggressive arch replacement doesn’t necessarily indicate reduced chances of reoperation or higher chances of survival, the extent of arch replacement must be judged based on patient condition rather than rather than pursuing more aggressive arch repair procedures.
Biomedical Sciences, Interdisciplinary
