Aortopathy research – UROP Spring Symposium 2022

Aortopathy research

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Katelyn Gilbert

Pronouns: she/her

Research Mentor(s): Bo Yang
Co-Presenter:
Research Mentor School/College/Department: Cardiac surgery / Medicine
Presentation Date: April 20
Presentation Type: Poster
Session: Session 1 – 10am – 10:50am
Room: League Ballroom
Authors: Katelyn Gilbert, Corina Ghita, Marc Titsworth
Presenter: 25

Abstract

The Bicuspid Aortic Valve (BAV) is located between the left atrium and left ventricle and has only two cusps; the Tricuspid Aortic Valve (TAV) is located between the right atrium and right ventricle and has three cusps. The purpose of this research is to analyze the surgical outcomes following acute type A aortic dissection (ATAAD) repair in BAV and TAV patient and to analyze the long-term growth rate of the descending aorta, abdominal aorta, and the distal aortic arch. The method used to complete this research was using a total of 605 patients from the Aortic Dissection Database that had surgical ATAAD repair. 438 of the 605 patients were used in the research (some patients were excluded due to history of connective tissue disease, 30-day postoperative mortality, and if the patient had less than two consecutive postoperative CT imaging studies). Those who were used were divided into two groups based on BAV or TAV morphology. Growth curves amongst the different segments of the distal aorta were utilized to perform cross-group comparative analyses; however, patients who had total surgical aortic arch replacement were excluded from this analysis. What was found was that the TAV group had higher rates of hypertension compared to the BAV group. The BAV group had a higher rate of aortic root replacement but slower rate of aortic root repair. Overall, there was no significant difference in the yearly aortic growth rate between the BAV and TAV groups of the aortic, abdominal, and descending arches. The yearly growth rate of the aortic, abdominal, and descending arches in BAV and TAV patients without connective tissue disease were similar after ATAAD repair.

Presentation link

Biomedical Sciences, Interdisciplinary

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