Breanna Campbell
Pronouns: she/her
Research Mentor(s): Adam Abraham
Co-Presenter:
Research Mentor School/College/Department: Orthopaedic Surgery / Medicine
Presentation Date: April 20
Presentation Type: Poster
Session: Session 2 – 11am – 11:50am
Room: League Ballroom
Authors: Breanna Campbell, Adam Abraham
Presenter: 4
Abstract
The mouse achilles tendon and human achilles tendon are both composed of Type 1 collagen. We are able to perform force and stress testing on the mouse achilles tendon, but the average cross-sectional area of the achilles must be determined to acquire material properties of the tendon. Information about the material properties allows us to examine the impact of different genotypes on the strength of the tendon during mechanical testing. This study included the execution and validation of a photogrammetry setup for tendon imaging. 360-degree images of four mouse achilles tendons were taken, with four sets of images taken of each. Each set of images was compiled to create a three-dimensional model of the tendon, which was analyzed to find the average cross-sectional area. The cross-sectional area of the models of the same tendon were compared to confirm precision, and the cross-sectional area of the models of different tendons were compared to confirm accuracy. Within the models of the same sample, the coefficients of variation between average cross-sectional areas were determined to be .533%, 7.85%, 14.2%, and 1.43%, respectively. For the average areas between different samples, the coefficient of variation was 13.8%, which is less than the typical 20% of variation between individuals in a population of the same species. Therefore, the developed photogrammetry procedure proved to be an accurate and precise process to model and acquire the cross-sectional area of the mouse achilles tendon. The photogrammetry can now be coupled with further testing to compare the material properties of achilles from different genotypes.
Biomedical Sciences
