Chiraag Balsara
Pronouns:
Research Mentor(s): Neehar Parikh
Co-Presenter:
Research Mentor School/College/Department: Internal Medicine Gastroenterology and Hepatology / Medicine
Presentation Date: April 20
Presentation Type: Poster
Session: Session 2 – 11am – 11:50am
Room: League Ballroom
Authors: Chiraag Balsara, Neehar Parikh
Presenter: 105
Abstract
Immunotherapy medications have become commonly used to treat many patients with various cancer types. Immunotherapy based regimens are approved to treat patients with hepatocellular carcinoma (HCC), the most common type of primary liver cancer. HCC most often occurs in the setting of cirrhosis of the liver. In the United States, the main causes of liver disease include alcohol-related liver disease, non-alcoholic fatty liver disease, and viral infection from Hepatitis C. There are some preliminary data to suggest that immunotherapy is less effective in patients with non-viral etiologies of liver disease. The purpose of this study is to investigate differences in response to immunotherapy depending on the cause of the underlying liver disease. We will retrospectively analyze patients at Michigan Medicine, with different etiologies of HCC, who have received immunotherapy-based regimen and compare outcomes. The primary outcomes of the study include of time to tumor progression, overall survival, as well as adverse events. These data will be important in making future treatment decisions for patients with HCC.
Biomedical Sciences, Interdisciplinary
