Advaith Thattai
Pronouns: He/him/his
Research Mentor(s): Allison Ho
Co-Presenter:
Research Mentor School/College/Department: Surgery / Medicine
Presentation Date: April 20
Presentation Type: Poster
Session: Session 4 – 2:40pm – 3:30 pm
Room: League Ballroom
Authors: Advaith Thattai, Jordan Wean, Randy Seeley
Presenter: 2
Abstract
Co-agonist drug treatments pave the way for diabetic drug development. While targeting receptors for GIP or GLP-1, co-agonism has been shown to provide more efficacious results while also limiting toxic side effects. The mechanism of action for dual incretin hormone agonism is through inhibiting GLP-1 receptor neurons in the hindbrain. Through dual incretin agonism, by testing mouse models, we are better able to better understand the changes in body weight, food intake, and toxic side effects by examining the effect of neuronal GIPR.
Biomedical Sciences, Interdisciplinary
