Jonah Mathisson
Pronouns: he / him
Research Mentor(s): Stephen Dowker
Co-Presenter:
Research Mentor School/College/Department: Acute Care Research Unit / Medicine
Presentation Date: April 20
Presentation Type: Poster
Session: Session 4 – 2:40pm – 3:30 pm
Room: League Ballroom
Authors: Jonah Mathisson, EMT, Stephen Dowker, BS, FF/EMT, Amanda Missel, PhD, RN
Presenter: 91
Abstract
Background: Early cardiopulmonary resuscitation (CPR) and application of automated external defibrillators (AED) are well-studied interventions for victims of out-of-hospital cardiac arrest (OHCA). However, there are limited data on the delivery of intranasal (IN) medication in OHCA. We aim to assess the effects of IN medication administration on CPR performance. Methods: We will conduct 30 OHCA simulations involving laypersons without OHCA response experience. Participants will be randomly assigned to a control group providing CPR and AED or an experimental group providing CPR, AED and IN medication administration. Both groups will receive instructions from a simulated 911 dispatcher. We will collect data to assess differences in intervention timing. Our primary outcomes will include time-to-first-shock, -compression, and -second-shock, and time-to-IN-medication-administration in the experimental group. Preliminary Results: We piloted the study with a preliminary sample of 2 control and 2 experimental participants. Participants in both groups were 100% white and 100% had received previous CPR training. The mean age in the control group and experimental groups were 35 years (yr) (SD: 15.6yr) and 54yr (SD: 12.7yr), respectively. The control group was 100% male, while the experimental group was 50% male. In the control and experimental group, time-to-first-shock was 191 seconds (s) (SD:05s) and 186s (SD: 33s), and time-to-second-shock was 341s (SD: 06s) and 340s (SD: 29s), respectively. Average time-to-first-compression was 420s (SD(control): 4s; SD(experimental): 33s) in both groups. The experimental group averaged 331s (SD:21s) for time-to-IN-medication-administration. Conclusion: Our preliminary assessment provides early findings suggesting the IN medication administration by laypersons during OHCA care may not impede other key interventions. These findings could contribute to the implementation of novel interventions for OHCA; however, additional study with a larger sample size and more robust analysis is needed to verify these findings.
Biomedical Sciences



