Monitoring Aortic Root Progression Using Imaging for ATAAD Patients – UROP Spring Symposium 2022

Monitoring Aortic Root Progression Using Imaging for ATAAD Patients

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Kush Amin

Pronouns: he/him/his

Research Mentor(s): Bo Yang
Co-Presenter:
Research Mentor School/College/Department: Cardiac surgery / Medicine
Presentation Date: April 20
Presentation Type: Poster
Session: Session 1 – 10am – 10:50am
Room: League Ballroom
Authors: Felix Orelaru, Faraz Longi, Rana-Armaghan Ahmad, Aroma Naeem, Xiaoting Wu, Karen M Kim, Shinichi Fukuhara, Himanshu Patel, Michael Deeb, Bo Yang, Kush Amin
Presenter: 27

Abstract

Studies tend to prioritize reoperation rates when determining aortic root progression in acute type A aortic dissection (ATAAD) patients after an aortic root repair (ARr) or aortic root replacement (ARR). However, we posit that assessing aortic root progression using postoperative imaging techniques such CTA provides a more accurate depiction. From 1996 to 2019, we collected imaging data for both the ARr group (n=332) and ARR group (n=194) after ATAAD procedure. Data regarding the postoperative aortic root growth rate, reoperation, and survival outcomes were collected. The ARr group had a higher proportion of zone-2 arch replacements (22% vs 11%) and patients with prolonged intubation (58% vs 49%). The ARR group had higher cardiopulmonary bypass time (266 minutes vs 203 minutes), aortic cross clamp time (214 minutes vs 128 minutes), concomitant coronary artery bypass graft surgery rate (7.7% vs 2.4%), and packed red blood cell transfusion (4 units vs 3 units). The average follow-up imaging was done in 4 years; aortic root growth rates (0.20mm/year vs. 0.18mm/year, p=0.75), 15-year survival rates (51% vs 52%, p=0.40), and 15-year reoperation rates (6.9% vs 5.9%, p=0.67) were not significantly different between ARr and ARR patients. The growth rate of the aortic root was significant for both root repair (0.20 mm/year, p=0.01) and replacement groups (0.18mm/year, p=0.003). Due to mortality risk or reoperation in out-of-network hospitals, reoperation rate does not accurately represent aortic root progression. Using aortic root diameter from imaging, we found minimal root progression in both ARr and ARR groups treated for ATAAD. Both ARr and ARR are sound methods to deal with ATAAD.

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Biomedical Sciences, Interdisciplinary

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