Apurva Vaddamani
Pronouns: she/her/hers
Research Mentor(s): Ajjai Alva
Co-Presenter: Croissette, Molly
Research Mentor School/College/Department: Internal Medicine/Hematology-Oncology / Medicine
Presentation Date: April 20
Presentation Type: Poster
Session: Session 1 – 10am – 10:50am
Room: League Ballroom
Authors: Apurva Vaddamani, Molly Croissette, Edward Green, Alyssa Ghose, Alicia Ali, Claire Knaus, Ajjai Alva
Presenter: 8
Abstract
Michigan Retrospective Immunotherapy Experience is a retrospective database at the University of Michigan with clinicopathologic features of all cancer patients who receive cancer immunotherapy including efficacy and side effects. We looked at the impact of COVID vaccination status on immunotherapy outcomes. Our cohort of 300 consecutive patients received immunotherapy between March 2020 – March 2021 and received at least 1 dose of an FDA-approved COVID-19 vaccine between December 2020 and March 2022. Because this study is still in the data collection phase, there are currently few results. However, it can be predicted and inferred from the current collection that the COVID vaccination has caused the severity and frequency of certain immunotherapy toxicities to be worsened. The impacts of the findings are important and relevant to those receiving immunotherapy treatment, especially during the time of the pandemic. Being able to correlate a worsening in the effects of the immunotherapy treatment to the vaccine could allow patients to be better informed prior to treatment or allow for medications themselves to be modified to limit the side effects that the patients experience.
Biomedical Sciences
