Necroptosis is a key precursor to histotripsy induced ferroptotic immune response – UROP Spring Symposium 2023

Necroptosis is a key precursor to histotripsy induced ferroptotic immune response

Katherine Buglak

Katherine Buglak photo

Pronouns: she/her

Research Mentor(s): Anutosh Ganguly
Research Mentor School/College/Department: Surgery / Medicine
Program: UROPF
Session: Session 3 (11:00am – 11:50am)
Authors: Katherine Buglak, Anutosh Ganguly, Brian Song, Natalie Gatteno, Ashley Ortenburg, Clifford Cho

Abstract

A study was conducted to investigate the relationship between necroptosis and ferroptosis, two different types of cell death, post-Histotripsy. Histotripsy is a non-invasive, non-thermal ultrasound based tumor ablation treatment. An in vivo experiment inhibiting necroptosis was conducted to explore its effects on ferroptosis.

Health Science

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