Mitigating Asymmetrical Electric Fields in Cellular Delivery/Removal via Memristive Technology – UROP Spring Symposium 2024

Mitigating Asymmetrical Electric Fields in Cellular Delivery/Removal via Memristive Technology

Jebril Thaxton

Pronouns: He/Him

Research Mentor(s): Albert Liu
Research Mentor School/College/Department: Chemical Engineering / Engineering
Program:
Authors: Mathew Manion, Jebril Thaxton, Albert Liu
Session: Session 1: 9:00 am – 9:50 am
Poster: 41

Abstract

The efficiency of cellular delivery and removal using Electroporation is highly dependent on the field strength. However, asymmetrical electric fields often pose significant challenges in achieving optimal outcomes. This study investigates the impact of edge effects on microfluidic devices and proposes a solution leveraging memristive technology. Memristive materials exhibit unique electrical properties, allowing them to dynamically adjust their resistance based on the charge history. Leveraging these characteristics, we hypothesize that memristive layers can effectively eliminate asymmetrical electric fields, thereby allowing uniform current distribution in cellular delivery/removal systems. This study not only sheds light on the detrimental effects of asymmetrical electric fields in cellular systems but also provides an avenue for their mitigation through memristive technology.

Engineering, Interdisciplinary, Physical Sciences

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