Multi-level influences on rural HPV vaccine hesitancy in the rural US: a scoping review – UROP Spring Symposium 2025

Multi-level influences on rural HPV vaccine hesitancy in the rural US: a scoping review

Ben Puzzuoli

Research Mentor(s): Sherri Sheinfeld Gorin
Mentor Department: Department of Family Medicine
Authors: Ben Puzzuoli, Sherri Gorin, Kelly Montgomery, Ben Puzzuoli
Session: Session 3 (11:00am – 11:50am)
Presentation Type: Poster 112

Abstract

Introduction. The Human Papillomavirus (HPV) vaccine is critical for preventing the spread of HPV, a sexually transmitted infection. The HPV is the cause of 90% of cervical and 70% of oropharyngeal cancers. The vaccine is generally administered to children ages 11-12, and is recommended for those aged 9-26 . The FDA has approved administration of the HPV vaccine to older individuals depending on their prior health history and risk to contract the virus, through a discussion with their healthcare provider. The vaccine is generally highly effective over time. The vaccine is unequally distributed, however, with rural residents experiencing higher incidence of both types of cancer with lower vaccination rates. Aims. The aim of this study is to conduct a scoping review of empirical studies of the HPV vaccine in the rural USA. Methods An informationist searched across 7 databases (e.g, OVID, Medline) for published empirical studies of the HPV vaccine between 2024-2025 using the following inclusion criteria: unduplicated record, rural, in the US, empirical study. Three hundred ninety seven articles were retrieved. Using the study inclusion criteria, and covidence software, groups of raters further reduced the number of studies. Finally, using a standardized rating form, at least two independent coders rated each of the remaining 61 studies. Coding differences were resolved by discussion with a third coder. Each of the coding categories (i.e., number of participants, study types, intervention types, and others) were summarized across all 61 papers. Findings (Study ongoing) Conclusions (Study ongoing)

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