Interdisciplinary – Page 29 – UROP Spring Symposium 2021

Interdisciplinary

A Comprehensive Review of Forms of Sexual Education and Analysis of an mHealth Comprehensive Sexual Education

The US has some of the highest rates of teen pregnancy among developing countries with approximately 200,000 babies born to teens aged 15 to 19 in 2016 (1,2). Additionally, nearly 50% of diagnosed STIs are seen in people under the age of 25 (3). These high rates of teen pregnancy and STIs may be due to abstinence-only sex education in schools, which some studies show have minimal effectiveness in preventing STIs and teen pregnancy (4). Michigan state policy requires an emphasis on abstinence, and some schools choose not to provide information on contraceptives at all (5). The purpose of this study was to assess whether abstinence-only sexual education provides the same teen level of education as comprehensive sexual education using a review of relevant literature to compare the two.

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Whole Health Evaluation for Veterans

Holistic forms of healthcare treatment are becoming increasingly important. Many research studies have been conducted on holistic treatment options for veterans, demonstrating their value and encouraging implementation. The federally funded Veterans Affairs (VA) Healthcare System, also the largest healthcare system in the USA, employs “Whole Health”, a holistic system of care, involving a diverse array of modalities, including yoga, acupuncture, meditation, tai chi, massage therapy, and more. This research seeks to evaluate the understanding, awareness, and treatment outcomes of Whole Health by those at VA, including employees, patients, relatives, and volunteers. A quantitative and qualitative Qualtrics survey was given to those at the Ann Arbor VA Healthcare System to analyze such by having participants rank themselves in categories like mental health, emotional health, spiritual health, and more. Survey-takers also identified which Whole Health modalities they have participated in. Currently, the research is ongoing. At the time of publication of this abstract, the data has been collected and preliminary analysis is in process. Specific, detailed, and final results will be available at the time of the Symposium presentation. Our team expects that the resulting data from the survey will indicate a strong understanding of the VA Whole Health system and its benefits. We anticipate that those who have utilized the offered VA modalities will report a greater health than those who haven’t. These results will demonstrate the value and relevance of holistic healthcare, specifically when treating veterans. In turn, our results will support the initiative to implement holistic medical treatment in more hospitals/healthcare systems worldwide and contribute to the academic discourse about the benefits of holistic healthcare.

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Whole Health Educational Evaluation for Veterans and VA Staff

“Whole Health Educational Resource Development and Evaluation for Veterans and VA Staff” A study was undertaken with the purpose of evaluating and identifying resource effectiveness in veterans or VA staff related to Whole Health usage. The federal government has taken interest in determining if Whole Health is a more effective healthcare care technique that can treat serious mental and physical conditions that can occur as a result of military engagement or treatment of military members. Review of Passport to Whole Health 3rd Edition 2018, videos on the VA Administration website, and mentor guidance helped prepare the development of a survey to be distributed. This survey is yet to be distributed to veteran and VA participants through online and physical means. Online through qualtrics and by hand for physical copies with the means of spreading the word through the VA Ann Arbor Healthcare System in Ann Arbor, MI. We are yet to determine the findings, but we expect to be able to determine pain points associated with the treatment and effective modalities as well. Based on these results we are to address and analyze the data to report our findings on Whole Health resources.

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Suppressing heterotopic ossification and fibrodysplasia ossificans progressiva in mouse models through targeting BMP type 1 receptor kinases

Fibrodysplasia Ossificans Progressiva (FOP) is a rare genetic condition distinguished by the development of bone in soft tissue, known as heterotopic ossification (HO). FOP is a gain-of-function mutation, causing substitution of an arginine by histidine (R206H) within BMP type 1 receptor ACVR1 protein. This disorder severely impacts an individual’s life, as it leads to body malformations and disabilities. While the exact mechanism of HO progression is still unclear, studies have found that HO development is accompanied with an increase of BMP-SMAD signaling and inflammation. In this research project, we aim to discover methods to decrease HO in FOP mouse models, by attempting to decrease BMP signaling. ACVR1, BMPR1a, and BMPR1b are BMP type 1 receptors. Our previous studies showed that BMP-SMAD dependent signaling is decreased by the knockout of BMPR1a or ACVR1 in specific tissues. By deleting one and/or multiple of these receptors, we predict that it will decrease BMP signaling, ultimately suppressing HO. We use the constitutively active ACVR1 model (caACVR1-Q207D), which develops massive HO within two weeks after activation of BMP signaling with tissue injury. But our study showed our anticipation was wrong. We found that the HO was not inhibited in ACVR1-Q207D mouse model by knocking out BMP type 1 receptors. Additionally, the BMP-SMAD dependent signaling pathway was not inhibited by knocking out BMP type 1 receptors in the HO mouse models. Due to the fact that the outcomes of this project did not support our initial hypothesis, we need to analyze other ways to decrease BMP signaling to suppress HO formation. This research hopes to bring us closer to finding the first effective treatment for FOP/HO, helping the individuals whose lives are permanently impacted by this genetic disease.

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Modeling cardiac aging with stem cell-derived cardiomyocytes carrying a mutation for advanced aging

Using various images taken through a confocal microscope, the area of the nuclei in the heart cells of mice were measured in an effort to compare two varieties of cells. Those that were extracted from mice suffering from Hutchinson Gilford Progeria Syndrome (HGPS), a severe and rare cardiovascular disease. Comparing these two types of cells provided a better idea of the meaningful ways in which cell morphology is different in regards to the presence of HGPS. Differences reflecting statistical significance were identified between the heart cells of “healthy” mice and those afflicted with HGPS. This data collection helps build upon the foundation and overarching goal of the lab which is to model cardiac aging through the use of stem cell derived cardiomyocytes.

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Leader Career Narratives

Emily Kagan Pronouns: She/Her Research Mentor(s): Elizabeth Trinh, PhD Student Research Mentor School/College/Department: Management and Organizations, Ross School of Business Presentation Date: Thursday, April 22, 2021 Session: Session 3 (1pm-1:50pm) Breakout Room: Room 4 Presenter: 7 Event Link Abstract For privacy concerns this abstract cannot be published at this time. Authors: Emily Kagan, Elizabeth Trinh

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White employers’ evaluations of same-race referrals: The role of perceived in-group favoritism

Racial inequality and discrimination are still pervasive in the U.S. labor market. While prior research finds that employers discriminate against Black and Latino jobseekers without referrals, we know less about how race affects how employers evaluate jobseekers’ same-race referrals. This is important because many jobseekers find employment through referrals; these referrals are typically of the same race as the applicant. To address this gap in literature, we conducted a survey experiment where we tested the differences in how employers evaluate the same-race referrals of White, Black, Hispanic and Asian job applicants. The analyzed data come from an empirical experiment conducted in the United States. White individuals (n = 635) with hiring and/or supervisory experience in their workplace were recruited through Amazon Mechanical Turk to participate in a survey experiment. Respondents were assigned a random racial group (Black, White, Hispanic, Asian) and were asked whether individuals of these racial groups prefer to refer individuals of their same race, or the best qualified job applicants. Respondents were then asked to explain their choice in their own words and their responses were coded into a fairly small number of categories. We found that while approximately half of the sample stated that Black and Hispanic employees prefer to refer applicants of their same race than the “best qualified” applicants, and approximately 1/3 reported the same for Asian employees, only 16% stated that whites prefer to refer white applicants rather than the best-qualified applicants. This suggests white hiring agents are more likely to dismiss non-whites’ same-race referrals””seeing them as a reflecting in-group bias rather than credibly signaling applicant quality””than whites’ same-race referrals. We also analyze the open-ended responses to examine mechanisms underlying these racial differences.

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Anti-AAPI Hate in the Coronavirus Pandemic: Which harassment incidents get the attention of American media?

As incidents of anti-Asian American hate have spiked since the beginning of the global coronavirus pandemic, leaders, advocates, and members of the Asian American Pacific Islander (AAPI) community feel there is not enough media attention given to this rise in racially-charged harassment (Marston). This project investigates the qualitative properties of the most frequently reported harassment incidents (FRHI). FRHIs are defined by appearing in American media at least ten times throughout 2020. FRHIs were compiled after analyzing a database composed of 2020 Newsbank and Proquest articles surrounding the issue of anti-AAPI hate.

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Virulent Hate: The Relationship between Anti-Asian Hate in the Covid-19 Pandemic and Population Proportion in California

In the United States, the start of the Covid-19 pandemic has brought an increase in racist incidents and attacks on Asian Americans and Pacific Islanders (AAPIs). Most recorded hate incidents have occurred in states with large populations of AAPIs like California and New York. This study investigates this relationship at the city level and considers the proportion of AAPIs in cities where hate incidents have occurred. Hate incidents are collected from news media reports and recorded in a database by a research team led by Dr. Melissa May Borja of the University of Michigan. The population of AAPIs in any given area in the United States is documented by the Census and American Community Surveys. This research study analyzes the AAPI population proportion in the areas where the most racist incidents have been reported and hypothesizes a direct relationship between the population of AAPIs and racist incidents.

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Lift Every Voice

The topic of my research is “lifting every voice”: a closer look at how individual voices can be amplified in local government to create widespread change. The project looks deeper at community organization at a local level using organizations aimed at reforming the idea of a town meeting on a national level. By examining different counties that these organizational programs have been implemented in, such as Surry County, Virginia, we are hoping to draw conclusions on the most effective way of community organizing at a local level to promote amplification of individual voices within low income communities. Through weekly meetings with my mentor, websites, databases, and books, I am piecing this information together in order to write a script for a video essay, which will be combined with photos, videos, and interviews. This video will be spread to promote the idea that this action must be taken at local levels with help from powerful individuals. I have found that the best way of amplifying individual voices is a reformed town meeting using electronic means, where people are divided into what Donald Anderson calls an Assembly, groups of 50 people with one leader and 7 subsections with their own leaders. Each group has individual advocates who come together and discuss changes that must be made in communities. These findings promote a coherent and concrete method of organizing people in low income areas. Although complex, these organizational structures must be implemented in order for people to participate directly in their government.

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