The Impacts of Nuclear Radiation on DNA Repair Machinery – UROP Spring Symposium 2021

The Impacts of Nuclear Radiation on DNA Repair Machinery

Yeniselis Morales


Pronouns: She/Her

Research Mentor(s): Lynn Carpenter, Lecturing Faculty
Research Mentor School/College/Department: Ecology and Evolutionary Biology /Molecular, Cellular, and Developmental Biology, College of Literature, Science, and the Arts
Presentation Date: Thursday, April 22, 2021
Session: Session 3 (1pm-1:50pm)
Breakout Room: Room 19
Presenter: 5

Event Link


The field of nuclear radiation has been analyzed through time in order to further quantify the effects of nucleotide ionizing particles both in the environment and humans. The focus is often to not only understand the health impacts of radiation exposure, but to also innovate preventive measures for a heightened risk for cancer development during long-term physical exposure to high levels of ionizing radiation. To date, researchers have focused on a wide range of organisms and exposure levels for radiation-focused studies, making it difficult to quantify and summarize the status of this field to date. We aim to produce a useful review that summarizes the status of this research while focusing on the DNA repair pathways currently used to improve radiation cancer therapy. In our review, we found that the ability to optimize DNA repair mechanisms can lead to a higher chance of radioresistance in our cells and can potentially serve as a clinical treatment for ionizing radiation-induced damage in our genomic DNA. Ultimately researchers feel this should allow enough time for the DNA repair mechanisms to correct the damage in an error-free and timely manner.

Authors: Yeniselis Morales
Research Method: Qualitative Study

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