Erica Griffin
Pronouns: she/her
Research Mentor(s): Colin Greineder
Co-Presenter:
Research Mentor School/College/Department: Emergency Medicine, Pharmacology, Biointerfaces Institute / Medicine
Presentation Date: April 20
Presentation Type: Poster
Session: Session 2 – 11am – 11:50am
Room: League Ballroom
Authors: Colin Greineder, Erica Griffin, Josh Goldberg, Olivia Bichoupan, Kelsey Grace
Presenter: 34
Abstract
Background: In the adult population, over 100,000 Americans die each year due to complications from Pulmonary Embolism, a blood clot that develops elsewhere in the body, often in the leg, and then travels to an artery in the lung. When compared to adults, acute PE is rare in the pediatric population, and there is little known about best practices for diagnosis or management in children. Objective: We sought to create a registry of acute PE cases diagnosed in the Children’s Emergency Services (CES) to define the treatment, outcomes, and follow up of children diagnosed with acute PE in the pediatric ED. Methods: Retrospective chart review of 320 PECT cases at a tertiary, academic, pediatric hospital (Mott). Results: For the 18 cases of acute PE diagnosed in the Mott ED, the average age was 18.2 years (IQR 16.9-19.9). 8/18 cases (44.4%) were male and 10/18 cases (55.6%) were female. The overall average hospital length of stay (LOS) was 3.4 days, but a statistically significant interaction between patient age and LOS was noted, with a mean LOS of 5.0 days (IQR 3.0-7.3) in children <18 years of age and mean LOS of 2.5 days (IQR 1.7-2.7) in children >= 18 years old (p = 0.02). 14/18 patients (77.8%) were treated with lovenox in the ED, while 2/18 (11.1%) were taken for interventional suction thrombectomy. Ultimately, 10/18 (55.6%) were discharged on lovenox, while the remaining children were discharge on apixaban. Outcomes were overall favorable, with no deaths at 30 days and 1/18 (5.6%) death at 90 days. Conclusions: Most acute PEs diagnosed in Mott were actually >= 18 years old. Most children were treated with lovenox in the ED and discharged on lovenox or a DOAC. A small percentage of children required mechanical thrombectomy and 1 child died at 90 days.
Biomedical Sciences
