Category: Gene regulation

microRNAs are a family of small, non-coding RNA molecules that have garnered increasing attention in the last 30 years. Their functionality as post-transcriptional off-switches make them important regulators of gene expression. This ability also suggests that microRNA therapies may have exciting clinical promise.

This video introduces the production and purpose of miRNA. It discusses the functions of proteins including Drosha, Dicer, and RISC. The produced miRNA functions in posttranscriptional regulation by blocking translation or cutting mRNA to silence gene expression.

This video introduces broad themes in eukaryotic gene regulation, including nucleosomes, enhancers, insulators, and a look back at the Gal system in yeast. To illustrate the most important polymer in life, it does it all with the help of polymer clay models!

This video uses beautiful animations to explain the process of genomic imprinting.

This video explains the E. coli lactose operon and the role of its components, including the repressor, operator and activator.