Genome Stability in Immortal Planarians – UROP Symposium

Genome Stability in Immortal Planarians

Soomin Lee

Pronouns: she/her

Research Mentor(s): Longhua Guo
Research Mentor School/College/Department: Molecular and Integrative Physiology; Geriatrics Center / Medicine
Program:
Authors: Soomin Lee, Longhua Guo
Session: Session 3: 11:00 am – 11: 50 am
Poster: 80

Abstract

Planarians are one of the only animals that can regenerate their entire bodies, and they are theoretically immortal. The Guo lab aims to study genome stability in different species of planarians. To achieve this goal, we karyotype 2 strains of Schmidtea polychroa to determine their ploidies. Then, we mate them and karyotype their offspring to know how their ploidies differ from that of their parents. The goal of the experiments is to understand how the planarians maintain their genome stability. Perhaps in many years, researchers can use what they have learned from planarians to discover how humans can maintain genome stability to prevent the harmful effects of aneuploidy.

Biomedical Sciences, Interdisciplinary

lsa logoum logo