Social genomic mechanisms of health disparities among Adolescent and Young Adult (AYA) cancer survivors – UROP Symposium

Social genomic mechanisms of health disparities among Adolescent and Young Adult (AYA) cancer survivors

Maria Dib

Pronouns:

Research Mentor(s): Bradley Zebrack
Research Mentor School/College/Department: Social Work / Social Work
Program:
Authors: Maria Dib, Bradley Zebrack
Session: Session 7: 4:40 pm – 5:30 pm
Poster: 71

Abstract

Adolescents and Young Adults (AYA) who are diagnosed with cancer from the ages of 15-39 tend to experience a distinctly different way of life. During these formative years, AYA’s may experience deep social isolation as well as health disparities and adversities, especially those living in low-income households or who are a part of minority groups. Do these health adversities affect gene expression and thus relate to an increase in the recurrence of cancer or other negative health outcomes? This research study aims to find a correlation between social genomics and comorbidities. This study examines the biological/molecular mechanisms by which social and environmental risk and resilience factors affect morbidity, mortality, and quality of life for young adult cancer survivors. There are two methods of data collection: online surveys and blood samples. These will be conducted every six months for two years. We will analyze our findings by keeping a track of the blood sample results as well as the survey results to see a correlation between the two. The survey records any financial, social, or physical disparities. The blood collection will be analyzed to discover if any genomic pathways have been induced, possibly due to any psychosocial or environmental factors. Currently, data collection is still underway, so no results can be drawn at this time. If social factors have a great impact on the patient’s health and wellbeing, then it will be more than necessary to ensure an improvement of cancer care. Any sort of discrimination or lack of resources in cancer care could contribute to a recurrence of cancer. Although it may be difficult to change certain disparities, it is still crucial to alleviate their pain. Cancer patients all across the world will benefit from this research program. If healthcare professionals and teams can recognize the impact of social determinants on a cancer patient’s health, extra precautions can be taken to improve their healthcare.

Biomedical Sciences, Interdisciplinary, Social Sciences

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