A Literature Review of Sex Differences in fMRI tasks used in MTwiNS Study
In previous clinical studies, males and females complete the same tasks; however, only a subset of those studies focus on sex-based differences in task interaction (Uhl et. al. 2007). Failure to look at sex differences in outcome and response may lead to aggregation of sex-related responses, causing neither sex to be accurately characterized (Institute of Medicine 1994). This presentation reviews the existing literature on sex differences for the following fMRI decision based tasks: Wack-A-Mole go no-go, Emotional go no-go, Event Related and Gender Rated Faces, Blocked Faces vs. Shapes, MID Reward, and Card Reward. All of these tasks are done at the Michigan Neurogenetics and Developmental Psychopathology (MiND) lab for their twin study (MTwiNS). MTwiNS aims to understand how antisocial behaviors are expressed in the brain. Antisocial symptomatology is more often present and studied in males, leading to many questions about how females with antisocial behaviors may differ (P Moran 1999).